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Proton Pump Inhibitors (PPI) Tied To Kidney Disease/Failure

Proton Pump Inhibitors (PPI) and Kidney Disease – What They Knew, When They Knew It

Heartburn (also called “acid reflux” or “gastroesophageal reflux disease/GERD”) is a common problem that plagues millions of people; so much so that in 2013, over 15 million Americans were believed to have been prescribed Proton Pump Inhibitors (PPIs) to treat this condition… and that number doesn’t even reflect the people using the over-the-counter versions. PPIs can include both the prescription and over-the-counter brands such as Nexium, Prilosec, Prevacid, and Protonix, but just because they’re easily accessible doesn’t mean that they’re safe. Millions of patients are now reporting that they are suffering from kidney disease or kidney failure after taking this popular medication.

What They Knew

Dr. Adriane Fugh-Berman, professor at Georgetown University Medical Center and the director of the university’s PharmedOut project, reports that 30 to 70 percent of PPI users don’t need to use these drugs. GERD can be simply treated through diet and lifestyle changes, and yet expensive marketing tactics and the over-prescribing of these medications are causing millions of patients to be at risk. In fact, in 2015 and 2016, more than $250 million was spent on advertising for over-the-counter and prescription PPIs. However, with so many patients taking this medication, doctors started to notice the connection between chronic kidney disease and patients who were taking PPIs.

When They Knew It

Many studies have proven the connection between PPIs and the increased risk of bone fractures and kidney injuries, and yet the pharmaceutical companies failed to warn patients of the increased potential for long term harm.

1996 – 2006 – In Australia, PPI prescription rose by 1,318% in just one decade.

2006 – The New England Journal of Medicine published their findings on the link between PPIs and acute interstitial nephritis which can cause sudden or long term kidney damage.

2011 – The advocacy group Public Citizen sent a petition to the FDA asking for a black box warning – the strongest warning available – alerting consumers of the potential for drug dependency and the increased risk of bone fractures. The FDA finally responded in 2014 and rejected the request.

2014 – FDA issues warning that PPIs can cause acute interstitial nephritis, which can result in permanent kidney damage or renal failure.

2016 – A study was published in the Journal of the American Medical Association which stated that those who suffered from kidney sensitivity problems were about 20 to 50 percent higher for those using PPIs than those who were not. Additionally, the Pharmaceutical Journal states that, “once a patient has taken a PPI for longer than a few weeks, acid hypersecretion can occur on discontinuation. This causes rebound symptoms, and frequently establishes a vicious cycle of drug reinitiation and long-term continuation.” This means that patients patients can become dependant on the drug as their body relies on it to manage their acid reflux symptoms.

2017 – Kidney International published a report that found that patients who were using PPIs had a 20 percent higher risk of developing chronic kidney disease and end-stage renal disease.

What Can You Do?

If you took prescription or over-the-counter Nexium, Prilosec, Prevacid, or Protonix and suffered from chronic kidney disease, renal failure, acute kidney injury, acute interstitial nephritis, bone deterioration, or bone fractures, you may be able to make a claim against the pharmaceutical manufacturers. These medications were sold for over 18 years before they warned patients of the potential for these dangerous complications. Call us today to see if you are eligible to make a financial claim.

PPI Warnings In The News

BREAKING (4/17/18): Leawood Attorney Looks to Give Big Pharma Heartburn with PPI Lawsuit

Leawood lawyer Kirk Goza filed suit against some of the biggest pharmaceutical companies in the United States, on behalf of 27 clients who took acid reflux medication that allegedly caused kidney damage.

Read Full Article

11/3/17: PPI Use Heightens Risk for Chronic Kidney Disease

People who use proton pump inhibitors, or PPIs, had a 1.4-fold increased risk for chronic kidney disease, according to an analysis of Taiwan national health insurance data.

Read Full Article

7/3/17: Some Heartburn Drugs Linked with Higher Risk of Death

Some heartburn drugs used by millions of Americans are associated with a higher risk of death, a new study suggests, but people on the drugs should talk with their doctor first before stopping the medicines, experts say.

Read Full Article

PPI Complaints & Damages

9/22/17: Armstrong v. Astrazeneca Pharmaceuticals, LP (NJ)

PPIs are used to reduce acid production in order to lower the risk of duodenal ulcer recurrence and NSAID-associated gastric ulcers as well as gastroesophageal reflux disease (GERD), dyspepsia, acid peptic disease, and other hypersecretory conditions, including Zollinger-Ellison Syndrome.

As a result of the defective nature of PPIs, persons who ingested this product, including Plaintiff, have suffered and may continue to suffer from kidney injuries including acute interstitial nephritis (“AIN”), acute kidney injuries (“AKI”), chronic kidney disease (“CKD”) and renal failure, also known as end-stage renal disease (“ESRD”).

Read Full Case

5/3/16: Mason v. Astrazeneca Pharmaceuticals, LP (IL)

As a result of the defective nature of PPIs, persons who ingested this product, including Plaintiff, have suffered and may continue to suffer from kidney injuries including acute interstitial nephritis (“AIN”), acute kidney injuries (“AKI”), chronic kidney disease (“CKD”) and renal failure, also known as end-stage renal disease (“ESRD”).

Read Full Case

4/30/14: Public Citizen Injunction Complaint to FDA

As a result of the defective nature of PPIs, persons who ingested this product, including Plaintiff, have suffered and may continue to suffer from kidney injuries including acute interstitial nephritis (“AIN”), acute kidney injuries (“AKI”), chronic kidney disease (“CKD”) and renal failure, also known as end-stage renal disease (“ESRD”).

Read Full Case

GET YOUR FREE Proton Pump Inhibitor (PPI) CASE REVIEW TODAY

Proton Pump Inhibitor (PPI) settlements are now being negotiated, but there is a limited window to pursue help. If you think you, a friend, or a family member may qualify, get your free case review today… before it’s too late!

  • * Submit now to learn if you may be eligible for a cash settlement or call (800) 511-3838 now.

Free Guide Download

The Step-By-Step Guide To Taking Action

How to File for Financial Settlement After Injury from an Unsafe Drug or Device

Free Guide Download

The Step-By-Step Guide To Taking Action

How to File for Financial Settlement After Injury from an Unsafe Drug or Device

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Periscope Group is not owned by or operated on behalf of any attorney or law firm. We are not affiliated with any drug or medical device companies. We do not host advertisements nor do we accept advertising requests. We are here to help YOU, the consumer, become better educated and supported. You pay absolutely nothing for our help. It’s as simple as that.

Periscope Group is not owned by or operated on behalf of any attorney or law firm. We are not affiliated with any drug or medical device companies. We do not host advertisements nor do we accept advertising requests. We are here to help YOU, the consumer, become better educated and supported. You pay absolutely nothing for our help. It’s as simple as that.

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