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Viagra Tied to Melanoma Cancer

Viagra and Melanoma – What They Knew, When They Knew It

Viagra (sildenafil citrate) is undoubtedly the most famous “little blue pill” in history. In 2016, Pfizer, the pharmaceutical company that makes Viagra, made $1.14 billion in U.S. sales and over $2 billion worldwide. With so many men taking this prescription, should the bottle carry a warning about the dangerous risk for melanoma (skin cancer)?

What They Knew

A study was published in JAMA Internal Medicine that determine that men who took Viagra had an 84 percent higher risk for having melanoma (skin cancer) than men who didn’t take the ED (erectile dysfunction) drug. Research began in 2000 when doctors questioned 26,000 men about their sexual health, if they used Viagra, how much time did they spend in the sun and if they had any genetic skin cancer risks (which included hair and eye color and mole growth). After ten years, it was found that the men who used Viagra were twice as likely to have melanoma.

So how can Viagra increase the risk for melanoma? One theory is that Viagra helps patients get an erection by suppressing the phosphodiesterase (PDE) 5A enzyme.This apparently mimics the activation of a mutation seen in melanoma. Simply put, if the PDE5A enzyme is lowered from the use of Viagra, there is a potential for melanoma cells to increase.

When They Knew It

While this study linking Viagra use to melanoma was published in 2014, there is still no warning on the label to make patients aware of the risk of skin cancer.  In June 2016, the US Food and Drug Administration (FDA) announced that it will “study the potential link between melanoma and erectile dysfunction (ED) drugs including sildenafil (Viagra)”, but as of yet, there have been no updates from the FDA.

What Can You Do?

If you took Viagra and currently have or have had melanoma, you may be able to receive compensation. You probably have expensive medicals bills and you might have had to take time off of work as a result of many doctors appointments, for recovery time or worse… Pfizer has been aware of the link of Viagra to melanoma for at least four years and they still fail to warn patients of the risk. Contact us today to see if you qualify to make a claim.

Viagra Warnings In The News

6/24/15: Men Who Take Viagra Increase Skin Cancer Risk By 21%: The Little-Known Link Between Money & Sex

A recent study has suggested that Viagra itself does not directly cause melanoma, but rather men who are prescribed the drug are more likely to have high skin cancer risk lifestyles. The finding raises an interesting idea and suggests that our sex lives and spending habits may be intrinsically linked.

The study, which is currently published in the Journal of the American Medical Association, is the product of an analysis of more than 20,000 male medical records. Among these men, 4,065 were found to have malignant melanoma between 2006 and 2012, and of these 435 had taken a drug to treat erectile dysfunction (ED). The data showed that taking an ED drug raised men’s risk of developing melanoma by 21 percent, but more importantly, the team found that the statistical risk of developing malignant melanoma did not increase with men who took more drugs for a longer period of time. As explained in the press release, this “dose relationship” between drug use and disease prevalence would be expected if the drugs were the direct cause of the cancer.

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Filed Viagra Complaints & Damages

7/25/16: Mayer vs. Pfizer Inc.

Unbeknownst to Viagra® users, studies have shown that the cellular activity providing the mechanism of action for Viagra® is associated with the development and/or exacerbation of melanoma. The American Cancer Society states that melanoma is “the most serious type of skin cancer.”

Several studies have linked the mechanism of action for Viagra® to cell mutation cultivating melanomagenesis, or the creation of melanocytes which develop into melanoma. A study published in 2011 found that treatment with Viagra® can promote melanoma cell invasion. Specifically, by inhibiting PDE5, Viagra® mimics an effect of gene activation and therefore may potentially function as a trigger for the creation of melanoma cells. A 2012 study published in the Journal of Cell Biochemistry also found that PDE5 inhibitors were shown to promote melanin synthesis, which may exacerbate melanoma development.

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LATEST ARTICLES

FDA Approves 1000X Stronger Opioid in the Midst of Addiction Crisis

We’ve all heard about the Opioid Crisis and maybe you’ve even had your doctor reduce or halt your prescription of Vicodin, Percocet, or Tylenol with Codeine (to name a few) in recent years.

Ironically, as prescriptions are decreasing concerning this highly addictive medication, the FDA has just approved Dsuvia, an opioid that is five to 10 times stronger than fentanyl and 500 to 1000 times more powerful than morphine.

Doesn’t this seem counterproductive to solving this drug epidemic that plagues the U.S.?

FDA Approves 1000 X’s Stronger Opioid in the Midst of Addiction Crisis

What is Dsuvia?

Dsuvia is made by AcelRx Pharmaceuticals, Inc. and is intended for “the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate,” explains Dr. Pamela Palmer, anesthesiologist and chief medical officer at AcelRx.

This new drug comes in pill form and is intended to dissolve under the tongue. Additionally, since it is such a potent medication, it’s only supposed to be distributed and monitored in medical settings to prevent drug abuse.

Other regulations include that a patient may only be on Dsuvia for 72 hours and the prescription will be required to have the same black-box warnings as all opioids concerning the risk of abuse, addiction, and overdose (but who reads a label when you’re admitted in a hospital?).

The Problem with Dsuvia

Opioid abuse has been rampant in the U.S. and offering a new opioid that is significantly stronger may only add fuel to the fire.

“It doesn’t seem reasonable to place another potent opioid on the market at this time, especially when we’re currently still writing 200 million prescriptions for opioids a year,” stated Dr. Raeford Brown, chair of the FDA advisory committee on analgesics and anesthetic drug products. “The need to put a drug like this on the market is not demonstrated.

The ability to manage that drug once it gets past the FDA is not demonstrated…. We know from looking at other potent opioids that have been put on the market in the last four years that once these drugs get past the FDA, there’s very little, if any, control over them, no matter what the sponsor says prior to the time they come on the market.”

More than 115 people die each day in the U.S. from an opioid overdose and opioid misuse costs our country approximately $78.5 billion a year. It seems obvious that offering a stronger drug will only create larger problems, especially when the FDA lacks the funding and manpower to perform post-market monitoring.

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Sources
“Amid deepening addiction crisis, FDA approves powerful new opioid”. CNN. Accessed November 5, 2018. https://www.cnn.com/2018/11/02/health/new-opioid-dsuvia-fda-approval-bn/index.html
“What is Dsuvia? What you should know about the new opioid drug that’s 10 times stronger than fentanyl”. ABC News. Accessed November 5, 2018. https://abcnews.go.com/Health/dsuvia-opioid-painkiller/story?id=58875487
“FDA ADVISORY COMMITTEE BRIEFING DOCUMENT”. FDA. Accessed November 5, 2018. https://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/AnestheticAndAnalgesicDrugProductsAdvisoryCommittee/UCM622858.pdf
“Opioid Overdose Crisis”. National Institute on Drug Abuse. Accessed November 5, 2018. https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis

California’s Deadly Camp Fire: How To Receive Financial Support

Once again fires have ravaged California’s forests and have left a multitude of residents displaced. Acres have been destroyed, there is just a charred footprint where thousands of homes once existed, and residents are shocked and wondering how will they ever pick up the pieces to their now broken lives. And for the fourth time in 12 months, faulty electrical equipment has been linked to the devastation.

California’s Deadly Camp Fire: How To Receive Financial Support

While all of the fires in the past year have touched our hearts, “Camp Fire” has hit one of our own team members here at Periscope Group. Laura, the manager of our Call Center, has been busily gathering clothes, toiletries, and other essentials for her parents who lost their home in Paradise, CA. This is their story.

Chris and Jenny’s Story

Chris and Jenny bought their retirement dream home in July 2018 off of Pentz Road in Paradise, CA. Just months later, on November 8, Chris walked outside and quickly noticed that the fire was so close that he could see the smoke swirling at the base of the flames. Just ten minutes later, Chris and Jenny tossed two backpacks containing three days’ worth of clothes, the contents of their safe, their two dogs, and a two-drawer metal filing cabinet into their cars. Chris advised Jenny to “make sure your bumper is touching my bumper the whole way down.” Amidst ash, flames, and wind, they desperately hurried to escape the quickly moving firestorm. Jenny would later describe it as moving through a “Biblical hell.”

They escaped to Chico to find refuge with a relative only to be relocated later that night since the fire was quickly spreading. They moved on to stay with Chris’ aunt who lives in Live Oak.

On the Sunday after their escape, a next door neighbor who was a city official went on an escorted expedition to find out what remained of her home. To her shock and heartbreak, her home had been leveled by the fire along with all of the neighboring homes… including Chris and Jenny’s.

Chris and Jenny have decided not to rebuild. Paradise is unique as compared to some of the other California fire locations in that it’s more of a “mom and pop” type town. There are no big businesses that will start over and many people don’t have the resources to pick up where the fire left off.

Other than the few items that they piled in the car, Chris and Jenny are now left with nothing. Photographs, childhood memories, and their dreams of retiring in Paradise have been reduced to ash. The emotional devastation has been as painful as the physical one.

How Could This Happen… Again?

While Chris and Jenny’s story is upsetting, they are in no way alone in this struggle to rebuild. Three fires last year – Butte, Tubbs, and Thomas – caused hundreds of thousands of acres to be wiped out, cost hundreds of millions of dollars, destroyed over 8,000 structures (most were private homes), and 25 people died. The current Camp Fire exceeds even these tragic numbers. As of November 13, 6,522 residential structures and 260 commercial buildings have been destroyed, 120,000 acres have been burned, and 42 people have lost their lives making this the largest and deadliest fire in California history.

What else do these fires have in common? All of them have been linked to malfunctioning equipment owned by PG&E or Southern California Edison (SCE). In this recent Camp Fire, an Electric Safety Incident Report stated that, “On November 8, 2018, at approximately 0615 hours, PG&E experienced an outage on the Caribou-Palermo 115 kV Transmission line in Butte County. In the afternoon of November 8, PG&E observed by aerial patrol damage to a transmission tower on the Caribou-Palermo 115 kV Transmission line, approximately one mile north-east of the town of Pulga, in the area of the Camp Fire.”   

What Can You Do About It?

We know that if you’re in this situation, you’re probably feeling heartbroken, devastated, lost, confused, and so much more and we want to help. Our legal team has assisted countless people who have lost everything due to mass fires and they can sort through insurance forms and other crucial paperwork to get the funding owed to you. Call (800) 511-3838 or contact us to speak with our Call Center today (and you can even request to speak to Laura!). We want to help you in any way we can.

 


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Image Source: KQED News

 

Is Your Doctor on Probation? Most Patients Don’t Know

Most patients either call their doctor’s office or visit a website to make an appointment. We think about what health complaints we want to share, write down any questions we may have, and just hope that we don’t have to sit in the waiting room too long.

Is Your Doctor on Probation? Most Patients Don’t Know

However, have you ever consider if your doctor ever had to undergo disciplinary action for sexual misconduct or for improperly prescribing a drug? After all, if they committed a crime like this and caught, wouldn’t their medical license be taken away? Not necessarily. Is your doctor on probation for misconduct?

The New California Law

It’s horrible that so many women have been assaulted, but a plethora of good has come from the female Olympic athletes who spoke out against their team doctor and the women who voiced their stories in the #MeToo movement.

One example of progress can be found in the new California law enacted in September 2018 called the Patient Right to Know Act. This law states that physicians are required to inform patients when they were put on probation for harming those under their care. There is already a public directory in place that shares this information, but most patients are unaware of its existence (if your doctor is in California, you can look for your doctor’s name here. For other states, conduct a Google search that says, “how can I find out if my doctor is on probation in {your state here}?” The website for your medical board should appear.)

With this new law in place, physicians on probation after July 1, 2019, are required to alert clients about their status before an appointment.

Doctors may be put on probation for the following reasons:

  • Sexual misconduct against a patient
  • Drug abuse that can be harmful to patients
  • A criminal conviction which resulted in harm to patients
  • Inappropriate prescribing resulting in patient harm

“It’s never made sense that doctors have had to tell their insurance companies, hospitals and clinics when they are put on probation, but not the people who are most at risk — their patients,” stated Lee Harris, president of the Consumer Attorneys of California.

According to the LA Times, surgeons, osteopaths, naturopathic doctors, chiropractors, podiatrists and acupuncturists are also bound by the new law.

The relationship between you and your doctor is important and you need to feel safe, heard, and cared for to receive the optimum care that you deserve. If you don’t feel this way about your doctor, it may be time to search for a new one. Furthermore, this only affects California. We think other states should follow their lead.

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Sources
“California doctors must tell patients if put on probation for sexual misconduct under new law”. LA Times. Accessed October 31, 2018. http://www.latimes.com/local/lanow/la-me-ln-doctor-probation-law-20180920-story.html
“New Law Requires Doctors on Probation to Disclose Discipline to Patients”. NBC San Diego. Accessed October 31, 2018. https://www.nbcsandiego.com/news/local/New-Law-Requires-Doctors-to-Disclose-Past-Discipline-to-Patients-493909811.html

Periscope Group is not owned by or operated on behalf of any attorney or law firm. We are not affiliated with any drug or medical device companies. We do not host advertisements nor do we accept advertising requests. We are here to help YOU, the consumer, become better educated and supported. You pay absolutely nothing for our help. It’s as simple as that.

Periscope Group is not owned by or operated on behalf of any attorney or law firm. We are not affiliated with any drug or medical device companies. We do not host advertisements nor do we accept advertising requests. We are here to help YOU, the consumer, become better educated and supported. You pay absolutely nothing for our help. It’s as simple as that.

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